Suesa's Science Challenge: A different day in a microbiology lab

This post is for the entry of Suesa's Science Challenge #suesas-sciencechallenge

For detail of the challenge please click Here

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Today will be another exciting day for drug discovery” I told myself
Chilling and walking over to my messy lab bench in the dark. Just having the light turn on for my bench. I love going back early in the morning before everyone else, this is when I could have the whole lab to myself. Me, only me and science, no one else.

I get ready to culture the bacteria in to the Brain Heart Infusion Broth, the medium that the bacteria enjoy. It also carries that distinctive, beefy smell from opening the bottle each time. I have always wanted to try them, should be something like a salty soup, best served hot probably~



Those little clinical bastards that once infected human, they were now asleep on the bloody agar kept at the 4’C fridge. All I have to do is to put them into the Brain Heart Infusion Broth, to shake them and wake them at 37’C for a few hours. They will go frenzy to thrive and be ready for experiments, that potential massacre waiting to happen to some of them, muwahahahaha.

After doing the cultures, its time to look at yesterday’s result. Please please please, please show me something that works, I told myself. Make my day!! Here I look to the left and compare to the right. Yes!! Some of the bacteria didn’t grown upon the addition of the certain drugs when compared to the controls. (Drum rolls sound) We Got Hits!!! New hopes for new drugs against multidrug resistant bacteria!!



While I am waiting for my bacteria to grow, its time to tidy those data, plenty time for lunch and sometime to game a little~ Work hard and play hard, right?

It is about time to get ready for the next screening,
Brain Hearth Infusion Broth – Checked,
Bacteria growth – Checked,
Small molecule drug libraries – Checked,
Robotic arm platform – Checked

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I talked to myself in Tony Stark’s tone. J.A.R.V.I.S. is that robotic arm platform system!!
J.A.R.V.I.S. pass me that,
J.A.R.V.I.S. add the Broth into the 96 wells plate,
J.A.R.V.I.S. add the drugs and control,
J.A.R.V.I.S. add the bacteria to the plates,
J.A.R.V.I.S. put everything into the incubator.

I wish this was all real, my J.A.R.V.I.S. isn’t “Just A Rather Very Intelligent System”, but more of “Just A Rather Veteran Integrated System”. Its semi-automatic, I need to take part in some steps to make sure things go smooth.

Anyway, things are done for the day, let’s see how things turn out tomorrow, tomorrow will be another exciting day. Let get all those hits for next round screening, for more potent compounds. Then study them in more depths!!
Hopefully something will come up good for animal testings and eventually to human clinical trials!!

It is dark in the night, another day in lab, while the drugs are doing different action to the bacteria, the bacteria are trying hard to resist them. I am pretty sure later on, for our drugs, one or two of those bastards will find ways to evade them. But until then, we should keep the drug discovery pipeline open. The mistake was made decades ago for stopping new antibiotics researches, and we face the antibiotics void now.

Bad bugs with no drugs, I am not going to let this happen to my child’s generation.


Hope you guys enjoy my day just like I do
I would also like to take this opportunity to prove you guys my identity, haha
This photo was taken at my university by my friend~



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Cheers~

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